H2O2-induced mitochondrial fragmentation in C2C12 myocytes
نویسندگان
چکیده
منابع مشابه
Poly(ADP-ribose)polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H2O2
Poly(ADP-ribose)polymerases (PARPs) are a family of NAD+ consuming enzymes that play a crucial role in many cellular processes, most clearly in maintaining genome integrity. Here, we present an extensive analysis of the alteration of mitochondrial morphology and the relationship to PARPs activity after oxidative stress using an in vitro model of human hepatic cells. The following outcomes were ...
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ژورنال
عنوان ژورنال: Free Radical Biology and Medicine
سال: 2010
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2010.08.024